Panadol Tablets Usage And Safety
Side Effects
Thrombocytopaenia, Anaphylaxis cutaneous hypersensitivity reactions including among others skin rashes, angiodema, stevens johnson syndrome, toxic epidermal necrosis, bronchospasm in patients sensitive to aspirin and other NSAIDs, hepatic dysfuction.
Drug Interactions
The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.
Indication
It provide fast and effective relief against: Headache , Migraine pain , Joint pain associated with Osteoarthritis , Muscle ache , Tooth ache , Period pain , Fever.
When not to Use
This product is contraindicated in patients with a previous history of hypersensitivity to paracetamol or excipients.
Panadol Tablets Warnings
Warning 1
Underlying liver disease increases the risk of paracetamol related liver damage. Patients who have been diagnosed with liver or kidney impairment must seek medical advice before taking this medication.
Warning 2
Cases of hepatic dysfunction/failure have been reported in patients with depleted glutathione levels, such as those who are severely malnourished, anorexic, have a low body mass index or are chronic heavy users of alcohol.
Warning 3
In patients with glutathione depleted states such as sepsis, the use of paracetamol may increase the risk of metabolic acidosis.
