Usage And Safety
Dosage
Dexamethasone , Chloramphenicol
Side Effects
Most commonly, itching, redness or swelling of the eyelid, foreign body sensation or appearance of other sign of irritation, missing before the initiation of treatment have been reported. There have been reports of burning and stinging in the eye and blurred vision.
Drug Interactions
Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines. Dexamphenicol should not be administered simultaneously with certain types of antibiotics (penicillin, cephalosporin, gentamicin, tetracycline, vancomycin, etc.), since these may decrease or inhibit the activity of chloramphenicol. This medicine should not be used if you are treated with medicines for diabetes (sulphonylurea agents), those for decreasing blood coagulation (coumarin derivatives), hydantoins, methotrexate, since impaired blood formation may occur. Co-administration of this medicine and non-steroidal anti-inflammatory drugs (diclofenac, indomethacin, etc.), intended for use in the eye, is undesirable if you have previously had inflammation of the cornea.
Indication
Dexamphenicol is indicated for the treatment of inflammations of the eye, where the use of corticosteroids is appropriate and in cases, where there is an existing infection or a risk of infection, caused by bacteria, susceptible to the action of chloramphenicol.
When not to Use
Do not use this medicine if you are allergic to chloramphenicol, dexamethasone or any of the other ingredients of this medicine .
Warnings
Warning 1
You need to know that long-term treatment with chloramphenicol, including when applied in the eye, may lead to suppression of the bone marrow function. The bone marrow is responsible for the formation of blood cells.
Warning 2
As with other antibiotics, prolonged use of chloramphenicol may lead to the development of non-susceptible microorganisms or fungi. In this case, your doctor will prescribe other, appropriate therapy. Dexamethasone, in turn, may mask the signs of such an infection or its exacerbation.
Warning 3
This medicine should not be used for more than 10 days. You must talk to your doctor if you do not feel better after 3 days from the initiation of treatment.
