Norvasc Tablets Usage And Safety
Dosage
Amlodipine Besylate
Side Effects
Amlodipine Besylate is well tolerated; the most commonly observed side effects were headache, edema, fatigue, nausea, flushing and dizziness.
Drug Interactions
Azole antifungals , erythromycin , cyclosporins , sildenafil , rifampicin , dantrolene , simvastatin , tacrolimus , other antihypertensives , grape fruit juice.
Indication
Amlodipine Besylate is indicated for the first line treatment of hypertension and can be used as the sole agent to control blood pressure in the majority of patients.Amlodipine Besylate is indicated for the first line treatment of myocardial ischemia whether due to fixed obstruction (stable angina) and/ or vasospasm/vasoconstriction (prinzmetal’s or variant angina) of coronary vasculature.
When not to Use
Amlodipine Besylate is contraindicated in patients with a known hypersensitivity to dihydropyridines.
Norvasc Tablets Warnings
Warning 1
Changes in Amlodipine Besylate plasma concentrations are not correlated with degree of renal impairment. Amlodipine Besylate may be used in such patients at normal doses.
Warning 2
Amlodipine Besylate half life is prolonged in patients with impaired liver function, the drug should therefore be administered with caution in these patients.
Warning 3
Safety of Amlodipine Besylate in human pregnancy or lactation has not been established.
