Side Effects
Common: Headache, dizziness, cough, throat irritation, nausea, dryness of mouth and gastrointestinal motility disorder.Uncommon: Blurred vision, mydriasis, intraocular pressure increased, eye pain, halo vision, conjunctival hyperemia, corneal oedema, glaucoma, anaphylactic reaction, hypersensitivity, angioedema of tongue, lips & face, palpitations, supraventricular tachycardia, bronchospasm, paradoxical bronchospasm, laryngospasm, pharyngeal oedema, dry throat, diarrhea, constipation, vomiting, stomatitis, rash, pruritus and urinary retention.Rare: Accommodation disorder, atrial fibrillation, heart rate increased and urticaria.
Drug Interactions
Administration of ipratropium bromide with beta-adrenergics and xanthine preparations may intensify the bronchodilator effect.Co-Administration of ipratropium bromide with other anticholinergic drugs should be avoided, as this may lead to an increase in anticholinergic adverse effects.
Indication
Ipratropium bromide is indicated as: - Bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. - Adjunct to beta2-agonists in the management of acute severe asthma.
