Rovista Tablets Usage And Safety
Side Effects
Headache, dizziness, constipation, nausea, abdominal pain, myalgia, asthenia, diabetic mellitus Pruritus, rash and urticaria , Hypersensitivity reactions including angioedema, myopathy, rhabdomyolysis, pancreatitis.
Drug Interactions
Coumarin anticoagulants , Gemfibrozil , antacid suspension containing aluminium and magnesium hydroxide , Niacin.
Indication
Rosuvastatin is indicated for the treatment of: Hyperlipidemia and Mixed Dyslipidemia As adjunctive therapy to diet to reduce elevated Total-C, LDL-C, ApoB, nonHDL-C, and triglycerides and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia.
When not to Use
Rosuvastatin is contraindicated:- In patients with hypersensitivity to rosuvastatin or to any of the excipients.- In patients with active liver disease including unexplained, persistent elevations of serum transaminases and any serum transaminases elevation exceeding 3x the upper limit of normal (ULN).
Rovista Tablets Warnings
Warning 1
Rosuvastatin should be used with caution in patients who consume substantial quantities of alcohol and/or have a history of chronic liver disease.
Warning 2
A dose reduction should be considered for patients on rosuvastatin therapy with unexplained persistent proteinuria and/or hematuria during routine urinalysis testing.
Warning 3
Rosuvastatin should be prescribed with caution in patients with predisposing factors for myopathy/rhabdomyolysis. . Such factors include: renal insufficiency, hypothyroidism, personal or family history of hereditary muscular disorders, previous history of muscular toxicity with another HMG-CoA reductase inhibitor or fibrate, alcohol abuse.
