Usage And Safety
Dosage
Glyceryl Trinitrate
Side Effects
Very common (may affect more than 1 in 10 people) : • Throbbing headache.Common (may affect up to 1 in 10 people) : •Spinning sensation, fall in blood pressure when seated or standing up, dizziness, drowsiness • lack of energy.Uncommon (may affect up to 1 in 100 people) : • Fainting • facial flushing • feeling or being sick • localised burning sensation • tongue blistering • circulatory collapse.
Drug Interactions
Sildenafil , tadalafil or vardenafil , heparin , N-acetylcysteine , long acting nitrates (isosorbide dinitrate, isosorbide mononitrate , amitriptyline, disopyramide, atropine and propantheline, tricyclic antidepressants , apomorphine , ergot alkaloids
Indication
It is indicated for the treatment of acute attacks of angina pectoris including variant angina and for the prophylaxis of such attacks.
When not to Use
It is contraindicated in patients who are hypersensitive to the active substance, to other nitro compounds, or to any of the excipients. Do not take Glyceryl Trinitrate tablets if you have anaemia.
Warnings
Warning 1
It should be used with caution in patients with cerebrovascular disease since symptoms may be precipitated by hypotension.
Warning 2
The use of medicinecould theoretically compromise myocardial blood supply in patients with left ventricular hypertrophy associated with aortic stenosis because of the detrimental effects of tachycardia and decreased aortic diastolic pressure.
Warning 3
If angina symptoms have not resolved after a total of three doses, the patient should be instructed to seek prompt medical attention
