Side Effects
Uncommon: may affect up to 1 in 100 people • Acne, dry skin, redness of the skin, increased sebum production, photosensitivity reaction, itching, rash, scaly rash, scaling of the skin, sunburn • Application site reactions such as burning, inflamed skin, dryness, redness of the skin Rare: may affect up to 1 in 1,000 people • Hypersensitivity • Underactive thyroid gland (symptoms may include fatigue, weakness, weight gain, dry hair, rough pale skin, hair loss, increased sensitivity to cold). • Headache • Eye irritation • Gastroenteritis (inflammation of any part of the gastrointestinal tract), nausea • Inflamed skin, herpes simplex (cold sore), rash macular (small, flat, red spots), skin bleeding, skin burning sensation, loss of skin pigmentation, skin irritation • Application site symptoms such as irritation, swelling, superficial skin damage, discolouration, itching, scaling • Feeling hot, pain
Drug Interactions
Sulphur, salicylic acid, benzoyl peroxide or rescinol , erythromycin or metronidazole, aminoglycosides, other antibiotics or corticosteroids .
When not to Use
Do not use : • If you are pregnant • If you are planning a pregnancy • If you are allergic to clindamycin, tretinoin, or any of the other ingredients of this medicine . • If you are allergic to lincomycin. • If you have a chronic inflammatory bowel disease (e.g. Crohn’s disease or ulcerative colitis). • If you have a history of colitis with past antibiotic use which is characterised by prolonged or significant diarrhoea or abdominal cramps.