Usage And Safety
Dosage
Cyproterone Acetate + Ethinyl Estradiol
Side Effects
Common side effects (may affect up to 1 in 10 people) : Feeling sick , stomach ache , putting on weight , headaches , depressive moods or mood swings , sore or painful breasts . Uncommon side effects (may affect up to 1 in 100 people) being sick and stomach upsets , fluid retention , migraine , loss of interest in sex , breast enlargement , skin rash, which may be itchy . Rare side effects (may affect up to 1 in 1,000 people) : Poor tolerance of contact lenses , losing weight .
Drug Interactions
Anti-epileptic agents, antibiotics, barbiturates and rifampicin , primidone, phenytoin, carbamazepine, oxcarbazepine , ritonavir, nevirapine, efavirenz , griseofulvin, ketoconazole , etoricoxib , theophylline , tizanidine
Indication
It is used to treat skin conditions such as acne, very oily skin and excessive hair growth in women of reproductive age.
When not to Use
• Preparations containing oestrogen/progestogen combinations should not be used in the presence of any of the conditions listed below. Should any of the conditions appear for the first time during their use, the product should be stopped immediately.• Concomitant use with another hormonal contraceptive • Venous thrombosis present or in history (deep venous thrombosis, pulmonary embolism) • Arterial thrombosis present or in history (e.g. myocardial infarction) or prodromal conditions (e.g. angina pectoris and transient ischaemic attack). • Presence or history of cerebrovascular accident
Warnings
Warning 1
It is not for use in men and should not be used in children.
Warning 2
Hypertension may occur in association with the use of oral contraceptives. Regular blood-pressure checks, including a pretreatment level, are advisable.
Warning 3
Prolonged amenorrhoea following the use of oral contraceptives may occur. Caution is advised where oligomenorrhoea or amenorrhoea have occurred in the past.
